One possibility is that autophagy facilitates the colorectal tumor-associate antigen (TAAs)-presenting process and exaggerates the specific immune epitope, such as VEGF (vascular endothelial growth factor), EGFR (epidermal growth factor receptor), TP53, or KRAS, which further boosts the peptide vaccines that target on these potential therapy antigens [123,124]. Here, EGFR is linked to neoplasm.