Reduction in BVRA protein levels was linked to abnormal activation of the IR/IRS1/AKT/GSK3β/GLUT4 pathway, which was related to poor glycometabolic control, as well as the presence of metabolic syndrome, liver steatosis, and inflammation of visceral adipose tissue in individuals with obesity and T2D [29,30,31,32]. The gene discussed is BLVRA; the disease is Obesity.