AKT1 and neoplasm: In this line, miR-199a-3p has been found to be involved in regulating several pathways that are associated with tumor progression, such as the PI3K/Akt pathway, MAPK pathway and Wnt signaling pathway, and it has been reported that an altered expression of mir-199a-3p is associated with a poor prognosis in certain types of cancer, such as breast cancer and hepatocellular carcinoma [82,83,84].