Chemotherapy-induced BC cells secrete multiple SEVs miRNAs, including miR-9-5p, -195-5p, and -203a-3p, simultaneously targeting the transcription factor One Cut Homeobox 2 (ONECUT2), which induce CSC traits to BC cells, which has been associated with tumor refractoriness and progression [170]. This evidence concerns the gene ONECUT2 and breast cancer.