Similarly, NLRC5-FL and NLRC5-SA caused only a small increase in MHC-I expression in EL4 lymphoma cells (Figure 1C), yet EL4-NLRC5-FL and EL4-NLRC5-SA cells formed significantly smaller tumors than EL4-vector control cells (Figure 2D–F). This evidence concerns the gene NLRC5 and lymphoma.