As NLRC5-SA upregulates MHC-I as strongly as NLRC5-FL, we evaluated the growth of B16 melanoma and EL4 lymphoma cells expressing NLRC5-SA, NLRC5-FL or NLRC5-control vector as tumors in syngeneic C57BL/6 mice. The gene discussed is FLT3LG; the disease is lymphoma.