IL1B and coronary artery disorder: Though there were no obvious differences with IL-1β cytokine between the preoperative and postoperative CAD cohorts, the main reason for us to target the IL-1β axis with selenium was that the levels of IL-1β are directly associated with circulating leucocyte frequencies, possibly signifying its pathological functions, including leucocyte endogenous mediators [82] among the postoperative CAD cohort.