TNF and coronary artery disorder: CAD patients who underwent on-pump bypass surgery exhibited increased systemic levels of (i) circulating neutrophils, (ii) neutrophil elastase [31], (iii) complement components (C3a and C5a) [32], (iv) platelet activating factors [33], (v) C-reactive protein (CRP) (an acute phase reactant), (vi) pro-inflammatory cytokines, TNF-α, IL-6, IL-8 [34], (vii) adhesion molecules (E-selectin, P-selectin, ICAM-1) [35], and cardiac troponin I [36,37,38].