Our data revealed significant upregulation of FOXO3a, ATM, P65, PINK1 and TNF-α genes among the radio-induced BCC patients compared to the non-radio-induced BCC group (p = 0.021 for each of the ATM, P65, PINK1 and TNF-α genes; p = 0.043 for FOXO3a) (Figure 3). This evidence concerns the gene RELA and skin basal cell carcinoma.