WNT1 and neoplasm: Similarly, miR-148b also serves as tumor-suppressing miRNA in HCC via targeting the WNT1 Wnt family member 1 protein that is involved in tumor growth [55], while miR-193a-5p significantly inhibits HCC formation and progression, via targeting the nucleolar- and spindle-associated proteins [56], which are involved in genome stability regulation and cell multiplication [57].