Notably, the addition of myristic acid to the control TF-relevant protein mixture yielded a POAG-shaped denaturation profile with a T1m and T2m of 65.4 and 78.3 °C, respectively (the average values for POAG TF were 64.5 and 79.3 °C) (Figure 3C). Here, TF is linked to open-angle glaucoma.