RAMP1 and COVID-19: While the most recent one [196] reported a direct correlation between circulating CGRP levels and disease severity, the previous ones [194,197] obtained different results: in particular, one found low serum CGRP levels in COVID-19 patients along with a high RAMP1 (receptor activity-modifying protein 1) lung expression [194], while the other [197] failed to find a direct correlation between this peptide and headache in moderate COVID-19 patients.