NSTCs express higher levels of VDAC, which can be combined with PFKP, a dominant isoform of PFK in human glioblastoma (GBMs), making it bind to the outer membrane of mitochondria, thus inhibiting the expression of phosphofructokinase, platelet (PFKP) in the cytoplasm and inhibiting its glycolysis reaction [157,159]. Here, PFKP is linked to glioblastoma.