Upregulation of YAP and TAZ in different cancers (oesophageal squamous cell carcinoma, head and neck squamous cell carcinoma bladder cancer, lung cancer) is associated with increased expression of stemness markers CD44, CD133, SOX2, SOX9, Nanog, ALDH, higher chemoresistance, higher expression of multi drug resistance efflux transport ATP-binding cassette transporter protein ABCG2 and more active colony formation [66]. Here, PROM1 is linked to cancer.