WNT5A and familial pancreatic carcinoma: Elevated expression of non-canonical Wnt ligands Wnt2 or Wnt5A in pancreatic cancer cells promotes stemness, since non-canonical Wnt drives the epithelial–mesenchymal transition, as well as increases chemoresistance: Wnt5A signalling contributes to cancer cell survivability by reducing the chemotherapy-induced apoptosis [60].