In addition, these CENPF-related genes exhibited the expression differences between normal and tumor tissues: the expression of TOP2A or KIF23 was significantly upregulated in LPS, while that of BAG1,PNPLA2, CRYL1 or GRN was significantly downregulated in LPS or MRCLPS compared to normal tissues (Figure S2). The gene discussed is CRYL1; the disease is neoplasm.