NOS2 and Alzheimer disease: The animals used were a triple transgenic Alzheimer’s disease model (3xTg-AD) in which the linalool-treated group (25 mg/kg, every 48 h, 3 months) showed a reduction in the inflammatory markers p38 MAPK, NOS2, COX-2, and IL-1β in the hippocampi and amygdalae.