In univariate analyses, low CADM4 expression (p = 0.002), advanced T category (p = 0.001), lymph node metastasis (p = 0.002), high AJCC stage (p < 0.001), lymphovascular invasion (p = 0.004), and perineural invasion (p = 0.004) were predictors of short OS. The gene discussed is CADM4; the disease is metastatic malignant neoplasm in the lymph nodes.