More recently, the Age, Biomarkers, Clinical history (ABC)-stroke score, which includes age, cardiovascular biomarkers (i.e., NT-proBNP and high-sensitivity cardiac troponin T), and clinical history (i.e., prior stroke/transient ischemic attack), has been shown to outperform the CHA2DS2-VASc score in its ability to predict stroke in patients with AF and Congestive heart failure, Hypertension, Age ≥ 75 years, Diabetes mellitus, Stroke (doubled) (CHADS2) score ≥2 [14]. This evidence concerns the gene NPPB and stroke disorder.