Among the pathways listed above, the activities of the adipocytokine-signaling pathway, ERBB-signaling pathway, and JAK-STAT-signaling pathway were the most strongly correlated with the OS in the ccRCC patients, and these three pathways shared many common core enrichment genes (Figure 5B,C, Table S6). The gene discussed is SOAT1; the disease is nonpapillary renal cell carcinoma.