Regarding TGFB2, while its expression is increased in the postmortem brains of patients with SCZ and psychotic BD, due to its promoter DNA hypomethylation [64], other studies have shown that TGFB2 is over-expressed in the neurons of patients with Alzheimer’s disease [89,90]. Here, TGFB2 is linked to early-onset autosomal dominant Alzheimer disease.