Based on our KEGG pathway GSEA analysis, we found a close correlation between COPZ1 and the tumor immune response pathways, such as TNF signaling pathway, Chemokine signaling pathway, T cell receptor signaling pathway, Toll-like receptor signaling pathway, NOD-like receptor signaling pathways, which indicated that COPZ1 may involve in the tumor immunity. Here, COPZ1 is linked to neoplasm.