The resulting subnetwork (Figure 1) included 9 genes: migraine-associated genes APOE, LRP1, CARF, CTIF, RNF213, and ECM1; LAMA2, which is associated with vestibular anomalies in mice; and the neurodevelopment-associated genes MYO5A and KLC2. The gene discussed is CARF; the disease is migraine disorder.