The analysis performed with the use of SHEsis software on the genotyping data for SNVs potentially associated with MetS or MetS with T2DM (Table 4) showed that all SNVs, except one polymorphism (rs3811787) located in the regulatory region of UCP1 gene, were in the strong LD (r2 = 1). This evidence concerns the gene UCP1 and type 2 diabetes mellitus.