While the variants are not pathogenic according to ACMG criteria, and we are not able to confirm the impact, if any, of these variants on the psychosis pathology of the children and adolescents in the EOP cohort, our findings provide additional support for a role of GRIN2A in EOP and neuropsychiatric disease and represent a partial replication of the SCHEMA consortium. The gene discussed is GRIN2A; the disease is psychotic disorder.