Intriguingly, analogous hypersensitivity to oxidative stress has been previously demonstrated in animal and cell culture models defective in Fanconi anemia [26,54,55,56,57] or excision repair cross complementation group 1 (ERCC1) [58] DNA repair pathway genes, conditions that were improved by antioxidant treatment [58,59]. Here, ERCC1 is linked to Fanconi anemia.