Human neuroblastoma SH-SY5Y cells used to mimic OS damage in vitro. Four groups: untreated Ctrl, H2O2-induced injury model, kaempferol treatment, and ginsenoside rh2 treatment. WB to detect Nrf2, Trx, and Akt1. TrxR activity was Measur with the Solarbio thioredoxin reductase activity Kit. The gene discussed is NFE2L2; the disease is neuroblastoma.