NFE2L2 and cancer: Test effect of Chinese herb couple Fuzi and Ganjiang (Aconitum carmichaelii Debx and Zingiber officinale Rosc) on NI (tested on cultured BV2 microglial cells; tested viability, LPS-induction), which in turn induces cancer-related fatigue (tumour inoculation). NO detected through NO2-, ROS, ELISA, IF, Nrf2 siRNA transfection of BV2 cells, WB, immunohistochemistry, Hippoc and cortex; 7 days post-inoculation, mice randomised into Ctrl, tumour-model, minocycline, low-, intermediate- and high-dose Fuzi and Ganjiang → FST, OFT, TST, and E + M → sacrifice