The study that used fish employed the Japanese rice fish, medaka (Oryzias latipes), both male and female, and the one that used nematodes used Caenorhabditis elegans, while of the two conducted on cell lines, one used the macrophage RAW26.7 line (primary CD14+ monocytes from human donors of both sexes transformed in macrophages through 1-week Colony Stimulation Factor-1 stimulation) and the other used human neuroblastoma SH-SY5Y cells. Here, CSF1 is linked to neuroblastoma.