S100A8 and gastric cancer: In a recent meta-analysis, CagA was the most common risk factor for non-cardial gastric cancer (OR = 3.22; 95%CI: 2.10–4.94), while patients infected with VacA-positive strains were associated with a doubled neoplastic risk (OR = 2.05; 95%CI: 1.67–2.52) [20].