The cellular mechanism of ucOCN regulating avian FLHS is still unclear, while it may be similar to the proposed signaling pathways identified in human NAFLD, including the mitogen-activated protein kinase (MAPK), nuclear factor-κB (NF-κB), hedgehog, AMP-activated protein kinase (AMPK), c-Jun-N-terminal kinase (JNK), and peroxisome proliferator-activated receptor (PPARs) [63,64,65]. This evidence concerns the gene MAPK8 and metabolic dysfunction-associated steatotic liver disease.