In fact, hepatocytic autophagy is known to be suppressed by adenosine kinase-mediated AMP formation and leucyl aminopeptidase over-expression [77,78]; acyl-CoA binding (ACB) protein has also been described as a suppressor of autophagy in breast cancer cells via its binding ability to phosphatidylethanolamine of the phagophore membrane, resulting in the inhibition of LC3 lipidation [79]. The gene discussed is LAP3; the disease is breast carcinoma.