BRAF and malignant colon neoplasm: We first explored expression of the genes encoding for the hub proteins identified in our study in the database of tumor tissues from 48 colon cancer patients with BRAFV600E mutation vs. 478 tumor samples without BRAF mutation in the Cancer Genome Atlas (TCGA) dataset (Colorectal Adenocarcinoma, TCGA, PanCancer Atlas) using the cBioPortal for Cancer Genomics (https://www.cbioportal.org/ accessed on 15 December 2022).