Apart from periodontitis and COVID-19, local (salivary) and systemic (serum) TNF-α/IL-6/IL-1β levels also increased in other inflammatory conditions, such as chronic oral erosive lesions and ulcers, and these cytokine levels were inversely proportional to the IL-10 that regulated epithelial healing [48,49]. The gene discussed is IL10; the disease is periodontitis.