GJB2 and Hodgkins lymphoma: Pathogenic variants in GJB2 can cause nonsyndromic autosomal recessive or dominant HL [26] and syndromic HL associated with skin disease [7], including palmoplantar keratoderma (PPK) with deafness [27], Vohwinkel syndrome [28], keratitis-ichthyosis-deafness (KID) syndrome [29], hystrix-like ichthyosis with deafness (HID) [30], and Bart–Pumphrey syndrome (BPS) [31].