S100A8 and ovarian cancer: Out of 61 cancer-associated FT sEV proteins, we identified several proteins that have a reported role in ovarian cancer or cancer in general, including fibronectin, S100 protein families (S100A7, S100A8, S100A9), integrin (ITGB1), heat shock proteins (HSP90), and versican core protein (VCAN), among others.