FBLN1 and Cognitive impairment: In addition to the evidence provided in our results (Fig. 2 and Fig. 3c, Supplementary Figs. 9 and 10), the FBLN1 gene has been associated with a rare genetic syndrome that includes multiple cognitive impairments, and protein levels of FBLN1 have been associated with altered risk for ischaemic stroke (Palumbo et al.