As shown in Fig. 8, IL-1β treatment significantly increased MMP9 expression in mouse tumor tissues on the basis of the results of qPCR (9.57 ± 0.26 vs. 1.08 ± 0.44, P < 0.0001) and western blotting (1.13 ± 0.07 vs. 0.21 ± 0.04, P < 0.0001). The gene discussed is IL1B; the disease is neoplasm.