This is consistent with the partial correlation calculations using bulk RNA expression data (source: Breast Cancer TCGA) in which expression of CD274 is linked to the presence of activated and resting CD4+ memory T-cells, M1 macrophages as well as neutrophils, and expression of CD70 is correlated with activated CD4+ memory T-cells and regulatory T-cells (Supplementary Table 8). The gene discussed is CD4; the disease is breast cancer.