SjS patients had lower absolute counts of B-cells in comparison to Sicca patients (p = 0.152), and a significant decrease was found in the absolute counts of CD19+CD27+ memory B-cells' in SjS (50 vs 66 cells/μl, p = 0.021), more pronounced in the CD19+IgD+CD27+ unswitched memory B-cells subset (23 vs 35 cells/μl, p = 0.009) (Table 2 and Supp 2). This evidence concerns the gene CD27 and Schwartz-Jampel syndrome.