The Pearson's chi‐square test and Student's t test showed that NIA‐present was significantly associated with small radiological solid component size (p = 0.0042), smaller C/T ratio (p < 0.0001), GGO presence (p < 0.0001), larger pathological whole tumor size (p = 0.0055), smaller pathological invasive area size (p < 0.0001), earlier p‐T factor (p < 0.0001), earlier p‐Stage (p < 0.0001), LPA (p < 0.0001), v negativity (p = 0.0009), and EGFR mutation positivity (p = 0.0429). This evidence concerns the gene EGFR and neoplasm.