Although the contribution of Ncr1+ ILCs, ILC1s in particular, to the control of B16 melanoma cannot be formally excluded, our observation that liver ILC1s are not reduced and the notion that NK cells are key to control this metastatic cancer model supports the relevance of Myc in conventional NK cells for maintaining the antitumor response (Victorino et al, 2015; Lopez-Soto et al, 2017; Howard et al, 2021). Here, NCR1 is linked to melanoma.