GNRH1 and breast cancer: Taking into account the favorable properties of LHRH peptide in drug delivery system, here, for the first time, we produced a fusion protein of BinB pore-forming domain (BinBC) and LHRH targeting peptide (LHRH-BinBC) via the peptide linker containing glycine and serine (GSG) to target the LHRH receptor-associated breast cancer cells.