In only one case, we suspected temporal arteritis, but this diagnosis was excluded due to normal superficial temporal artery Doppler ultrasound, normal erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and a normal complete blood count; autoantibodies such as antinuclear antibodies, ANCAs, and rheumatoid factor were also negative. The gene discussed is CRP; the disease is temporal arteritis.