Acute endurance exercise causes hypercoagulability, as demonstrated by higher levels of coagulation Factor VIII, thrombin–antithrombin III complex (TAT), prothrombin fragments 1 and 2 (F1 + F2), fibrinogen, and fibrinopeptide A, as well as shorter activated partial thromboplastin time (aPTT) and nonactivated partial thromboplastin durations [71,72]. Here, F8 is linked to thrombophilia.