Additionally, it has been reported that the ectopic expression of miR-19a-3p, a member of the miR-17-92 cluster, contributes to HCC metastasis and sorafenib chemoresistance by modulating the expression of phosphatase and tensin homolog (PTEN) and PTEN-dependent pathways [105]. The gene discussed is PTEN; the disease is hepatocellular carcinoma.