BRAF and melanoma: Melanoma instances are characterized by excessive activation when the growth factors stimulate tyrosine kinase receptors after binding with it and resulting in the activation of the RAS family monomeric G protein, Neuroblastoma RAS viral oncogene homolog (NRAS) and serine/threonine kinases, v-Raf murine sarcoma viral oncogene homolog B (BRAF) BRAF.