Although these animals did have renal abnormalities which may have contributed to the poor condition and failure to thrive of Pdgfrb-Cre+/−;Gnaqfl/fl;Gna11−/− mice, the bowel appeared normal and mice with mesenchymal Gαq/11 deletion induced in adulthood had normal kidneys. This evidence concerns the gene PDGFRB and Failure to thrive.