There are strong experimental studies reported the classical 1,25(OH)2D3 and novel CYP11A1‐derived hydroxyderivatives have immunomodulatory and anti‐inflammatory effects that can reduce the cytokine storm by enhancing the innate immune response and modulating the acquired immune system response to COVID‐19.53, 54, 55, 56. The gene discussed is CYP11A1; the disease is COVID-19.