To investigate the factors influencing LVDD in ART‐naive PLWHA, we performed a univariate regression analysis with the following factors as independent variables: age (per 10‐year increase), BMI, hypertension, diabetes, smoking history, duration of HIV infection, TC, TG, HDL‐C, LDL‐C, viral load (log‐transformed), and CD4 count. The gene discussed is CD4; the disease is hypertensive disorder.