In the present meta‐analysis, our pooled data showed that IL‐6 could forecast all‐cause mortality risk in dialysis patients, which could be explained as follows: (1) increased IL‐6 indicates an upregulation of inflammatory status in dialysis patients, which could be attributed to infection (including catheter‐related infection, peritonitis, bloodstream infection, and so on), metabolic syndrome, and severe pneumonia; these factors could lead to mortality in dialysis patients.50, 51, 52, 53, 54. This evidence concerns the gene IL6 and infection.