The literature harbors many inflammatory/immunological conditions including inflammatory bowel diseases, psoriasis, systemic lupus erythematosus, Sjögren's syndrome, antiphospholipid syndrome, acute graft‐versus‐host disease, immune thrombocytopenic purpura, Aicardi−Goutieres syndrome, Kikuchi−Fujimoto, and hand, foot, and mouth diseases, in which significant increases in IFI27 expression have been reported.39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50. The gene discussed is IFI27; the disease is Sjogren syndrome.