Two innate immune response genes drew special attention, namely CLEC12A and IFI27 in the DEG sets of the class comparisons M versus C, O versus C, and V versus C. Besides their potential functional significance in BS pathogenesis, CLEC12A and IFI27 both were among the top 10 DEGs (Table 6). The gene discussed is CLEC12A; the disease is Bloom syndrome.