Atopic dermatitis (AD) is reported to be correlated with AD‐HIES (job's syndrome), IPEX, Netherton syndrome, PGM3 deficiency, DOCK8 deficiency, STAT3 GOF, Omenn syndrome, activated leukocyte cell adhesion molecule (ALCAM), and hypereosinophilia.6, 11, 63. The gene discussed is ALCAM; the disease is hyper-IgE syndrome.