WEE1 and small cell lung carcinoma: In conclusion, high expression of the key regulatory factor‐Wee1 and further catalyzing H2BY37ph, which produces a crosstalk between H2BY37ph and H2BK120, leading to elevated levels of H2BK120ub that in turn promote DSB repair, resist the mitotic catastrophe otherwise caused by excess DSB, and ultimately lead to treatment resistance in SCLC.