The effects of munronoid I, which is extracted and purified from Munronia sinica on LPS-induced inflammation in mice showed administration of munronoid I (10 mg/kg, IV) significantly inhibited LPS-induced infiltration of inflammatory cells, scored of lung tissue damage, and also the production of IL-1β and IL-6 in BALF of ALI mice [69]. The gene discussed is IL1B; the disease is acute respiratory distress syndrome.